Cannabinoids as Therapeutics

Endogenous and Synthetic Cannabinoids as Therapeutics in Retinal Disease

The functional significance of cannabinoids in ocular physiology and disease has been reported some decades ago. In the early 1970s, subjects who smoked Cannabis sativa developed lower intraocular pressure (IOP). This led to the isolation of phytocannabinoids from this plant and the study of their therapeutic effects in glaucoma. The main treatment of this disease to date involves the administr...

Cannabinoids: Forensic Toxicology and Therapeutics

Cannabinoids as Therapeutics for Non-Melanoma and Melanoma Skin Cancer

Skin cancer has a significant impact on the health care system of many societies. The most common types of skin cancer are Non-Melanoma Skin Cancer (NMSC) and melanoma. In the United States, NMSC incidence is greater than all other cancers combined. Although death is a rare outcome of NMSC, recurrence is fairly common. In contrast, melanoma is highly metastatic, chemoresistant and is often leth...

Future of Cannabis and Cannabinoids in Therapeutics

This study reviews human clinical experience to date with several synthetic cannabinoids, including nabilone, levonantradol, ajulemic acid (CT3), dexanabinol (HU-211), HU-308, and SR141716 (Rimonabant®). Additionally, the concept of “clinical endogenous cannabinoid deficiency” is explored as a possible factor in migraine, idiopathic bowel disease, fibromyalgia and other clinical pain states. Th...

A systematic review of gold nanoparticles as novel cancer therapeutics

Objective(s):The current systematic study has reviewed the therapeutic potential of gold nanoparticles as nano radiosensitizers for cancer radiation therapy.   Materials and Methods: This study was done to review nano radiosensitizers. PubMed, Ovid Medline, Science Direct, SCOPUS, ISI web of knowledge, Springer databases were searched from 2000 to September 2013 to identify appropriate studies....